(E) | 1. |
下列那一類風濕免疫疾病的遺傳機率最高?
|
A. | 全身性紅斑狼瘡 |
B. | 類風濕性關節炎 |
C. | 修格連氏症候群(Sjogren's syndrome) |
D. | 全身性硬皮症 |
E. | 僵直性脊椎炎 |
|
(B) | 2. |
退化性關節炎(Osteoarthritis)甚少侵犯的關節為
|
A. | Distal interphalangeal joints |
B. | Wrist joint |
C. | Knee joint |
D. | Hip joint |
E. | Spine |
|
(A) | 3. |
下列先天性免疫不全症(primary immunodeficiencies)中,主要以抗體不足或缺乏(antibody deficiency)為特徵之疾病是那一種?
|
A. | Common variable immunodeficiency |
B. | Adenosine deaminase deficiency |
C. | Chronic granulomatous disease |
D. | Severe combined immunodeficiency |
E. | Di George's syndrome |
|
(B) | 4. |
每一類風濕病常有典型特殊的X光變化;請問下列配對,何者為誤?
|
A. | Rheumatoid arthritis --- marginal erosion |
B. | Osteoarthritis --- osteoporosis |
C. | Psoriatic arthritis --- " Pencil - in - cup " appearance |
D. | Ankylosing spondylitis --- syndesmophyte |
E. | Pseudogout --- chondrocalcinosis |
|
(A) | 5. |
膠原疾病(collagen disease)常侵犯腎臟造成嚴重後果。請問最易侵犯腎小管(renal tubule)內造成腎小管性酸血症(renal tubular acidosis)之疾病是
|
A. | 修格連氏症(Sjogren's syndrome) |
B. | 全身性紅斑狼瘡 |
C. | 皮肌炎(dermatomyositis) |
D. | 硬皮症(scleroderma) |
E. | 類風濕性關節炎 |
|
(B) | 6. |
下列關於血管炎與其臨床特徵之配對中,何者為誤?
|
A. | Temporal arteritis --- high ESR |
B. | Henoch-Schonlein Purpura --- IgG immune complexes |
C. | Wegener's granulomatosis --- anti-neutrophil cytoplasmic antibody |
D. | Polyarteritis nodosa - Hepatitis B antigenemia |
E. | Churg - Strauss disease - eosinophilia |
|
(B) | 7. |
下列關於硬皮症(scleroderma)在心臟血管系統所造成的異常之描述,那一項是不正確的?
|
A. | 可發生肺高壓而導致右心衰竭 |
B. | 可發生心絞痛,而且冠狀動脈攝影檢查常可見狹窄異常 |
C. | 雷諾氏現象(Raynaud's phenomenon)可發生在耳或鼻處 |
D. | 可發生心包膜積水(Pericardial effusion) |
E. | 可發生心肌纖維化而導致左心衰竭 |
|
(D) | 8. |
肌腱(tendon)或韌帶(ligament)附著於骨(bone)之處稱之為enthesis。下列那一類風濕病是以enthesis發炎(enthesopathy)為其臨床最主要的特色?
|
A. | 痛風(gout) |
B. | 退化性關節炎(osteoarthritis) |
C. | 類風濕性關節炎(rheumatoid arthritis) |
D. | 僵直性脊椎炎(ankylosing spondylitis) |
E. | 敗血性關節炎(septic arthritis) |
|
(A) | 9. |
被認為可以改變類風濕性關節炎病程的藥物(Disease-modifying anti-rheumatic drugs, DMARD)包括
1. anti-malarials
2. corticosteroid
3. indomethacin
4. sulfasalazine
5. D-penicillamine
|
A. | 1, 4, 5 |
B. | 2, 5 |
C. | 2, 3, 4 |
D. | 3, 4, 5 |
E. | 1, 2, 3 |
|
(C) | 10. |
可經由尿酸過度產生(urate overproduction)而造成高尿酸血症(hyperuricemia)之臨床疾病包括
1. lead intoxication
2. hemolytic anemia
3. diabetic ketoacidosis
4. lymphoma
5. psoriasis
|
A. | 1, 2, 3 |
B. | 2, 3, 5 |
C. | 2, 4, 5 |
D. | 3, 4 |
E. | 1, 4 |
|